Article

The molecular architecture of the desmosomal outer dense plaque by integrative structural modeling

2023-06-14

Abstract excerpt

Desmosomes mediate cell-cell adhesion and are prevalent in tissues under mechanical stress. However, their detailed structural characterization is not available. Here, we characterized the molecular architecture of the desmosomal outer dense plaque (ODP) using Bayesian integrative structural modeling via the Integrative Modeling Platform. Starting principally from the structural interpretation of an electron cryo...

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Literature Corpus work: 11ad12a0-72e4-5dc8-aad0-60415fbef6cc
DOI: 10.1101/2023.06.13.544884

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