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Genetic Alterations Associated with Colistin Resistance Development in Escherichia coli.

Microbial drug resistance (Larchmont, N.Y.) - 1 Aug 2024

Alsahlani Fatemeh, Haeili Mehri

Abstract excerpt

Background: The increased incidence of infections due to multidrug-resistant Gram-negative bacteria has led to the renewed interest in the use of 'forgotten' antibiotics such as colistin. In this work, we studied the chromosomal colistin resistance mechanisms among laboratory-induced colistin-resistant Escherichia coli isolates. Methods: Three colistin-susceptible (ColS) clinical isolates of E. coli assigning to...

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PMID: 38905152
DOI: 10.1089/mdr.2024.0026

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