Article

Generation of porcine PK-15 cells lacking the <i>Ifnar1</i> gene to optimize the efficiency of viral isolation

2023-07-28

Abstract excerpt

Because pigs are intermediate or amplifying hosts for several zoonotic viruses, the pig-derived PK-15 cell line is an indispensable tool for studying viral pathogenicity and developing treatments, vaccines, and preventive measures to mitigate the risk of disease outbreaks. However, we must consider the possibility of contamination by type I interferons (IFNs), such as IFNα and IFNβ, or IFN-inducing substances, suc...

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Literature Corpus work: 10e40117-b7a8-5c9c-84d3-c89bbcb98299
DOI: 10.1101/2023.07.28.550964

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