Article

Generation of a porcine cell line stably expressing pig TMPRSS2 for efficient isolation of viruses from pigs with respiratory diseases

2023-10-15

Abstract excerpt

Pigs are important animals for meat production but can carry several zoonotic diseases, including Japanese encephalitis virus, Nipah virus, and influenza viruses. Several Orthomyxoviridae and Coronavirinae respiratory viruses require cleavage of envelope proteins to acquire viral infectivity and consequently need a host protease or the addition of exogenous trypsin for efficient propagation. Host TMPRSS2 is a ke...

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Identifiers and source

Literature Corpus work: 98450bbc-229e-5885-8882-9b68267681a8
DOI: 10.1101/2023.10.14.562371

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