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Live Zika virus chimeric vaccine candidate based on a yellow fever 17-D attenuated backbone

2018-02-27

Abstract excerpt

Zika virus (ZIKV) recently dispersed throughout the tropics and sub-tropics causing epidemics associated with congenital disease and neurological complications. There is currently no commercial vaccine for ZIKV. Here we describe the initial development of a chimeric virus containing the prM/E proteins of a ZIKV epidemic strain incorporated into a yellow fever 17-D attenuated backbone. Using the versatile and rapid...

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Identifiers and source

Literature Corpus work
10de8cce-781e-5125-9cff-e1405145e805
DOI
10.1101/272625
Open publication

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Live Zika virus chimeric vaccine candidate based on a yellow fever 17-D attenuated backboneDOI 10.1101/272625
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