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An effective live-attenuated Zika vaccine candidate with a modified 5′ untranslated region

1 Apr 2023

Abstract excerpt

Abstract Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has caused devastating congenital Zika syndrome (CZS), including microcephaly, congenital malformation, and fetal demise in human newborns in recent epidemics. ZIKV infection can also cause Guillain-Barré syndrome (GBS) and meningoencephalitis in adults. Despite intensive research in recent years, there are no approved vaccines or antiviral...

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PMID: 37005424
DOI: 10.1038/s41541-023-00650-w

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