Article

The human functional genome defined by genetic diversity

2016-10-21

Abstract excerpt

<h4>ABSTRACT</h4> Large scale efforts to sequence whole human genomes provide extensive data on the non-coding portion of the genome. We used variation information from 11,257 human genomes to describe the spectrum of sequence conservation in the population. We established the genome-wide variability for each nucleotide in the context of the surrounding sequence in order to identify departure from expectation at...

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Literature Corpus work: 6222b2ca-e64f-5c4c-b355-5e9ffcd3b773
DOI: 10.1101/082362

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