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Hyperpiliation reduces <i>Pseudomonas aeruginosa</i> pathogenicity by impeding type III secretion

2021-01-29

Abstract excerpt

<h4>ABSTRACT</h4> Type IVa pili (T4aP) are important virulence factors for many bacterial pathogens. Previous studies suggested that the retraction ATPase, PilT, modulates pathogenicity due to its critical role in pilus dynamics and twitching motility. Here we use a Caenorhabditis elegans slow killing model to show that hyperpiliation, not loss of pilus retraction, reduces virulence of Pseudomonas aeruginosa st...

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Literature Corpus work
10c47037-4b4c-5999-b4ed-ae46771ecabc
DOI
10.1101/2021.01.28.428742
Open publication

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Hyperpiliation reduces <i>Pseudomonas aeruginosa</i> pathogenicity by impeding type III secretionDOI 10.1101/2021.01.28.428742
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