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Article

Pseudomonas aeruginosa type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activity.

PLoS pathogens - 1 May 2018

Marko Victoria A, Kilmury Sara L N, MacNeil Lesley T, Burrows Lori L

Abstract excerpt

Type IV pili are expressed by a wide range of prokaryotes, including the opportunistic pathogen Pseudomonas aeruginosa. These flexible fibres mediate twitching motility, biofilm maturation, surface adhesion, and virulence. The pilus is composed mainly of major pilin subunits while the low abundance minor pilins FimU-PilVWXE and the putative adhesin PilY1 prime pilus assembly and are proposed to form the pilus...

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Identifiers

PMID: 29775484
DOI: 10.1371/journal.ppat.1007074
PMCID: PMC5979040

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