Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Separation of Pseudomonas aeruginosa type IV pilus-dependent twitching motility and surface-sensing responses.

mBio - 12 Nov 2025

Barnshaw Rebecca, Harvey Hanjeong, McCallum Matthew, Lazarou Tomas, Nguyen Sheryl, Qaderi Ikram, Tran Veronica, Roberge Nathan, Geiger Christopher, O'Toole George A, Howell P Lynne, Burrows Lori L

Abstract excerpt

Many functions of Pseudomonas aeruginosa type IVa pili, including twitching motility and surface sensing, depend on dynamic cycles of filament assembly and disassembly powered by the cytoplasmic ATPases PilB, PilT, and PilU. Deletion of pilT results in loss of twitching and pilus-specific bacteriophage susceptibility, while non-twitching pilU mutants remain susceptible to pilus-specific phages, indicating that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Crystallography, X-Ray

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclic AMP

Share to Fimbriae, Bacterial

Share to Fimbriae Proteins

Share to Mutation

Share to Phylogeny

Share to Pseudomonas aeruginosa

Source

Open in PubMed Open full text

Identifiers

PMID: 41055394
DOI: 10.1128/mbio.02521-25
PMCID: PMC12607626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Separation of Pseudomonas aeruginosa type IV pilus-dependent twitching motility and surface-sensing responses.PMID 41055394Read ↗

Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa.Semantic proximity Read ↗

Hyperpiliation reduces <i>Pseudomonas aeruginosa</i> pathogenicity by impeding type III secretionSemantic proximity Read ↗

Novel proteins that modulate type IV pilus retraction dynamics in Pseudomonas aeruginosa.Semantic proximity Read ↗

FimX, a multidomain protein connecting environmental signals to twitching motility in Pseudomonas aeruginosa.Semantic proximity Read ↗

The repertoire of resistance mutations selected by a Pseudomonas aeruginosa type IV pilus-targeting lytic bacteriophage.Semantic proximity Read ↗

The <i>Pseudomonas aeruginosa</i> PilSR two-component system regulates both twitching and swimming motilitiesSemantic proximity Read ↗

<i>Pseudomonas aeruginosa</i> type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activitySemantic proximity Read ↗

How Bacteria Use Type IV Pili Machinery on Surfaces.Semantic proximity Read ↗

The repertoire of resistance mutations selected by a <i>Pseudomonas aeruginosa</i> type IV pilus-targeting lytic bacteriophageSemantic proximity Read ↗

Minor pilins of the type IV pilus system participate in the negative regulation of swarming motility.Semantic proximity Read ↗

Pseudomonas aeruginosa type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activity.Semantic proximity Read ↗

Delayed onset and heterogeneous collective organization characterize twitching motility in <i>Acinetobacter baumannii</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.