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Indirect pharmacology of Amorphophallus rivieri Durieu in pancreatic ductal adenocarcinoma: immune-dependent macrophage remodeling and amino acid-related metabolic alterations

2026-05-07

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Pancreatic ductal adenocarcinoma (PDAC) is characterized by a profoundly immunosuppressive tumor microenvironment, making host-mediated indirect therapeutic strategies particularly relevant. Among stromal immune populations, tumor-associated macrophages (TAMs) are key mediators of immune suppression and may serve as an intermediate biological layer linking the...

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Literature Corpus work
1091ab1e-eb8f-5840-be77-cf75e55aac4a
DOI
10.21203/rs.3.rs-9321051/v1
Open publication

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Indirect pharmacology of Amorphophallus rivieri Durieu in pancreatic ductal adenocarcinoma: immune-dependent macrophage remodeling and amino acid-related metabolic alterationsDOI 10.21203/rs.3.rs-9321051/v1
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