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Unveiling the Immunological Terrain of Pancreatic Ductal Adenocarcinoma: Strategies to Prompt Immunotherapy from Mendelian Randomization

2024-03-21

Abstract excerpt

<title>Abstract</title> <p>Pancreatic ductal adenocarcinoma (PDAC) remains a formidable challenge in oncology, characterized by its immunosuppressive tumor microenvironment (TME) and resistance to immune checkpoint inhibitors (ICIs). This study leverages Mendelian randomization (MR) to elucidate the causal relationships between PDAC and a comprehensive array of immune cell traits, bacterial traits, inflammatory f...

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Literature Corpus work
fea353d7-1cdb-59ca-9196-fd83ec2f98bc
DOI
10.21203/rs.3.rs-4000359/v1
Open publication

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