Article
Essential role of GATA3 in regulation of differentiation and cell proliferation in SK-N-SH neuroblastoma cells
29 Oct 2014
Abstract excerpt
Neuroblastoma is a common solid malignant tumor of the sympathetic nervous system, which contributes to 15% of cancer‑related mortality in children. The differentiation status of neuroblastoma is correlated with clinical outcome, and the induction of differentiation thus constitutes a therapeutic approach in this disease. However, the molecular mechanisms that control the differentiation of neuroblastoma remain...
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