Article
CDK inhibitors reduce cell proliferation and reverse hypoxia-induced metastasis of neuroblastoma tumours in a chick embryo model
2018-08-31
Abstract excerpt
Neuroblastoma is a paediatric cancer with a poor prognosis. This is in part due to the widespread metastasis at time of presentation, which is refractory to current treatment modalities. New therapeutic agents that can control not only tumour growth but also metastasis are urgently needed. One current therapeutic option used in the clinic is differentiation therapy with retinoic acid, where the terminal differenti...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 08969991-dd73-51d1-800a-fb03fea7bc3f
- DOI
- 10.1101/405639