Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential aminoacylase expression in neuroblastoma

2 Dec 2010

Abstract excerpt

Neuroblastoma, a cancer of the sympathetic nervous system, is the most common extracranial solid tumor in children. MYCN amplification and increased BDNF/TrkB signaling are features of high-risk tumors; yet, only ˜25% of malignant tumors display these features. Thus, the identification of additional biomarkers and therapeutic targets is essential. As aminoacylase 1 (ACY1), an amino acid deacetylase, is a putative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics and Neurodevelopmental Disorders
Share to Neuroblastoma Research and Treatments
Share to Neuroendocrine Tumor Research Advances

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21128244
DOI: 10.1002/ijc.25798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential aminoacylase expression in neuroblastomaPMID 21128244Read ↗

Amino Acid Metabolism Subtypes in Neuroblastoma Identifying Distinct Prognosis and Therapeutic Vulnerabilities.Semantic proximity Read ↗

Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma.Semantic proximity Read ↗

The Oncogenic Role of γ-Aminobutyrate Aminotransferase in Human Tumor: A Pan-Cancer AnalysisSemantic proximity Read ↗

Inhibition of fatty acid synthesis induces differentiation and reduces tumor burden in childhood neuroblastomaSemantic proximity Read ↗

Dihydropyrimidinase‐like protein 3 expression is negatively regulated by <scp>MYCN</scp> and associated with clinical outcome in neuroblastomaSemantic proximity Read ↗

Two opposing gene expression patterns within <i>ATRX</i> aberrant neuroblastomaSemantic proximity Read ↗

RNA N6-methyladenosine modification is required for miR-98/MYCN axis-mediated inhibition of neuroblastoma progressionSemantic proximity Read ↗

Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastomaSemantic proximity Read ↗

The polyamine metabolism genes <i>ornithine decarboxylase</i> and <i>antizyme 2</i> predict aggressive behavior in neuroblastomas with and without <i>MYCN</i> amplificationSemantic proximity Read ↗

Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cellsSemantic proximity Read ↗

Defining Pathological Activities of ALK in Neuroblastoma, a Neural Crest-Derived CancerSemantic proximity Read ↗

Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.