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Article

TGFBR3 loss and consequences in prostate cancer

27 Dec 2006

Abstract excerpt

BACKGROUND: Resistance to transforming growth factor-beta (TGF-beta) is important in tumorigenesis. TGF-beta resistance mechanisms in prostate cancer are not well understood. METHODS: We have conducted a systematic analysis of TGF-beta pathway components with a meta-analysis of seven microarray studies using Oncomine and evaluated the results of TGFBR3 expression in prostate cell lines. Furthermore, we knocked...

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PMID: 17192875
DOI: 10.1002/pros.20526

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