Article

MicroRNA-194 promotes lineage plasticity in advanced prostate cancer

2019-09-12

Abstract excerpt

<h4>ABSTRACT</h4> MicroRNA-194 (miR-194) promotes prostate cancer metastasis, but the precise molecular mechanisms by which it achieves this are unknown. Here, by integrating Argonaute high-throughput sequencing of RNA isolated by crosslinking immunoprecipitation (Ago-HITS-CLIP) with RNA sequencing and exon-intron split analysis, we defined a 163-gene miR-194 “targetome” in prostate cancer. These target genes wer...

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Literature Corpus work: e04ec4da-e39d-5eb3-8dd0-77633b47f2f7
DOI: 10.1101/752709

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