Article

Dscam1 promotes blood cell survival in <i>Drosophila melanogaster</i> through a dual role in blood cells and neurons

2020-09-26

Abstract excerpt

Down Syndrome Cell Adhesion Molecule 1 (Dscam1) is a receptor-like cell adhesion molecule that is conserved across the animal kingdom, but its roles in hematopoiesis remain unknown. Dscam1 related genes in vertebrates and invertebrates are key regulators of neuron morphogenesis and neuronal tiling. In Drosophila , Dscam1 in addition has roles in blood cells (hemocytes) in innate immunity and phagocytosis of patho...

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Literature Corpus work: 104a6111-8b2d-5058-a1bf-33da16aed337
DOI: 10.1101/2020.09.26.314997

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