Article

Allele-specific Effects of Three-dimensional Genome Architecture in Hybrid Pigs

2022-12-21

Abstract excerpt

<title>Abstract</title> <p> In diploid mammals, allele-specific three-dimensional (3D) genome architecture may lead to imbalanced gene expression. Through ultradeep <italic>in situ</italic> Hi-C sequencing of three representative somatic tissues (liver, skeletal muscle, and brain) from hybrid pigs generated by reciprocal crosses of phenotypically and physiologically divergent Berkshire and Tibetan pigs, we unc...

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Literature Corpus work: 103c30d4-c113-5da2-9e5e-26acc8887b35
DOI: 10.21203/rs.3.rs-2392032/v2

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