Article
Dissecting Allele-Specific Expression (ASE) in Landrace × Meishan Cross Pig Fetal-Placental Tissues: Distribution, Functional Split, and Mechanisms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 15 Jul 2026
Zhang Jinbi, Xu Shiyong, Wu Wangjun, Zhang Lifan, Jiang Aiwen, Shen Ming, Tao Jingli, Liu Honglin, Pan Zengxiang
Abstract excerpt
Allele-specific expression (ASE) is a key regulatory mechanism linking genetic variation to phenotypic diversity. This study conducted a genome-wide ASE analysis in embryonic (brain, kidney, liver) and extraembryonic (chorion) tissues of Landrace × Meishan crossbred pigs. By integrating DNA sequencing of parental and F1 hybrids and RNA-sequencing of F1 tissues, a high-resolution ASE landscape was built via strict...
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