Article
Characterizing structural variants based on graph-genotyping provides insights into pig domestication and local adaption.
Journal of genetics and genomics = Yi chuan xue bao - 1 Apr 2024
Li Xin, Liu Quan, Fu Chong, Li Mengxun, Li Changchun, Li Xinyun, Zhao Shuhong, Zheng Zhuqing
Abstract excerpt
Structural variants (SVs), such as deletions (DELs) and insertions (INSs), contribute substantially to pig genetic diversity and phenotypic variation. Using a library of SVs discovered from long-read primary assemblies and short-read sequenced genomes, we map pig genomic SVs with a graph-based method for re-genotyping SVs in 402 genomes. Our results demonstrate that those SVs harboring specific trait-associated...
Topics
- Swine
- Animals
- Genotype
- Domestication
- Genome
- Genomics
- Phenotype