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Article

Enhancer-promoter interaction maps provide insights into skeletal muscle-related traits in pig genome.

BMC biology - 9 Jun 2022

Li Jingjin, Xiang Yue, Zhang Lu, Qi Xiaolong, Zheng Zhuqing, Zhou Peng, Tang Zhenshuang, Jin Yi, Zhao Qiulin, Fu Yuhua, Zhao Yunxia, Li Xinyun, Fu Liangliang, Zhao Shuhong

Abstract excerpt

BACKGROUND: Gene expression programs are intimately linked to the interplay of active cis regulatory elements mediated by chromatin contacts and associated RNAs. Genome-wide association studies (GWAS) have identified many variants in these regulatory elements that can contribute to phenotypic diversity. However, the functional interpretation of these variants remains nontrivial due to the lack of chromatin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35681201
DOI: 10.1186/s12915-022-01322-2
PMCID: PMC9185926

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