Article

Mapping the Prosthetic-Host Interactome: From Systemic Inflammation to Biological Integration in Mesh-Enhanced Therapies (MET)

2026-06-03

Abstract excerpt

<h4>Background: </h4> Despite reducing hernia recurrence, synthetic meshes often trigger persistent foreign body responses (FBR). Mesh Enriched Therapies (MET), incorporating autologous cellular components (MSCs, PRP, SVF), can regeneratively reprogram the host-prosthetic interactome. <h4>Methods:</h4> Following PRISMA-ScR guidelines, a systematic search of PubMed, Embase, and Scopus (2000–2025) was conducted. We...

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Literature Corpus work: 3ab16d60-841b-5ec2-b1d1-e9c8d9523f48
DOI: 10.20944/preprints202606.0261.v1

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