Article

Identification of smoking-enabled blood miRNA regulatory networks

2026-06-27

Abstract excerpt

Cigarette smoking induces complex signaling disruptions that contribute to diseases such as COPD and lung cancer, yet the molecular mechanisms underlying these effects remain incompletely understood. To address this gap, we analyzed peripheral blood from 3190 COPDGene participants using LIONESS and PUMA and constructed miRNA-mRNA regulatory networks associated with smoking status. Comparing networks for active ver...

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Literature Corpus work: 10341355-e0ad-5f49-9727-6b4a66644aa1
DOI: 10.64898/2026.06.26.733220

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