Article

Integrative genetic and genomic networks identify microRNA associated with COPD and ILD

2022-08-09

Abstract excerpt

<h4>ABSTRACT</h4> Chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) are clinically and molecularly heterogeneous diseases. We utilized clustering and integrative network analyses to elucidate roles for microRNAs (miRNAs) and miRNA isoforms (isomiRs) in COPD and ILD pathogenesis. Short RNA sequencing was performed on 351 lung tissue samples of COPD (n=145), ILD (n=144) and controls (n...

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Literature Corpus work: dd04d104-1d53-5f2c-a2b5-94e91978c01e
DOI: 10.1101/2022.08.07.22278496

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