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Clinical whole-genome sequencing identifies NSD3 as the correct fusion partner of NUP98 in a patient with acute myeloid leukemia and t(8;11)(p11.2;p15): a case report

2022-02-22

Abstract excerpt

<h4>Background: </h4> Only rare cases of acute myeloid leukemia (AML) have been shown to harbor a t(8;11)(p11.2;p15.4). This translocation is believed to involve the fusion of NSD3 or FGFR1 with NUP98; however, apart from targeted mRNA quantitative PCR analysis, no molecular approaches have been utilized to define the chimeric fusions present in these rare cases. Case Presentation Here we present the case of a 51-...

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Literature Corpus work: 101971a0-520b-58df-87e7-4d1c2de1bda4
DOI: 10.21203/rs.3.rs-1374871/v1

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