Article

Junctophilin-2 physically interacts with ryanodine receptor type 2 for peripheral coupling of mouse cardiomyocytes

2020-04-06

Abstract excerpt

<title>Abstract</title> <p>Background: Ryanodine receptor type 2 (RyR2) mediate Ca 2+ release from the endoplasmic and sarcoplasmic reticulum (ER and SR), which is involved in the peripheral coupling of mouse cardiomyocytes, and thereby plays an important role in cardiac contraction. Junctophilin-2 (JPH2, JP2) is anchored to the plasma membrane (PM) and membranes of the ER and SR, and modulates intracellular Ca 2...

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Literature Corpus work: 0fe7e316-a1e6-538d-9053-f2a158071f69
DOI: 10.21203/rs.3.rs-20484/v1

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