Article
The junctophilin family of proteins: from bench to bedside.
Trends in molecular medicine - 1 Jun 2014
Landstrom Andrew P, Beavers David L, Wehrens Xander H T
Abstract excerpt
Excitable tissues rely on junctional membrane complexes to couple cell surface signals to intracellular channels. The junctophilins have emerged as a family of proteins critical in coordinating the maturation and maintenance of this cellular ultrastructure. Within skeletal and cardiac muscle, junctophilin 1 and junctophilin 2, respectively, couple sarcolemmal and intracellular calcium channels. In neuronal...
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