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Genomic Diversity and Runs of Homozygosity in Bernese Mountain Dogs.

Genes - 4 Mar 2023

Letko Anna, Hédan Benoît, Snell Anna, Harris Alexander C, Jagannathan Vidhya, Andersson Göran, Holst Bodil S, Ostrander Elaine A, Quignon Pascale, André Catherine, Leeb Tosso

Abstract excerpt

Bernese mountain dogs are a large dog breed formed in the early 1900s in Switzerland. While originally farm dogs that were used for pulling carts, guarding, and driving cattle, today they are considered multi-purpose companion and family dogs. The breed is predisposed to several complex diseases, such as histiocytic sarcoma, degenerative myelopathy, or hip dysplasia. Using whole-genome sequencing (WGS) data, we...

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Cattle
Dogs
Genome
Genomics
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 36980922
DOI: 10.3390/genes14030650
PMCID: PMC10048372

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