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<i>Borrelia burgdorferi</i> Secretes c-di-AMP as an Extracellular Pathogen-Associated Molecular Pattern to Elicit Type I Interferon Responses in Mammalian Hosts

2024-08-16

Abstract excerpt

<h4>ABSTRACT</h4> Borrelia burgdorferi ( B. burgdorferi ), an extracellular spirochetal pathogen, elicits a type-I interferon (IFN-I) response that contributes to the pathology of Lyme disease, including the development and severity of Lyme arthritis. However, the specific Pathogen-Associated Molecular Patterns (PAMPs) of B. burgdorferi responsible for triggering the IFN-I response are not well understood. Prev...

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Literature Corpus work
0fa7bac6-db6a-5041-8049-90248a060aa2
DOI
10.1101/2024.08.13.607721
Open publication

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<i>Borrelia burgdorferi</i> Secretes c-di-AMP as an Extracellular Pathogen-Associated Molecular Pattern to Elicit Type I Interferon Responses in Mammalian HostsDOI 10.1101/2024.08.13.607721
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