Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS Cov2 infection

Abstract excerpt

The COVID-19 pandemic is posing an unprecedented threat to the whole world. In this regard, it is absolutely imperative to understand the mechanism of metabolic reprogramming of host human cells by SARS Cov2. A better understanding of the metabolic alterations would aid in design of better therapeutics to deal with COVID-19 pandemic. We developed an integrated genome-scale metabolic model of normal human bronchial...

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• Bioinformatics and Genomic Networks
• Diet and metabolism studies
• Liver Disease Diagnosis and Treatment
• Metabolomics and Mass Spectrometry Studies

Identifiers and source

Literature Corpus work

77815f07-00ae-5145-a5b0-f165be5fdb88

DOI

10.1101/2020.11.29.402404