Article

Adhesion to VCAM1 and P-selectin Predict Time-to-Resolution (TTR) of Vaso-Occlusive Crisis

2022-10-21

Abstract excerpt

Sickle cell disease (SCD) is characterized by frequent and unpredictable vaso-occlusive crises (VOCs) resulting in increased morbidity and mortality. Reliable biomarkers that predict the onset and progression of VOCs in SCD are unavailable, thus the existing standard of care is more focused on VOC intervention as opposed to VOC prevention. Sickle blood cells contribute to VOCs by adhering to the endothelium and ag...

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Literature Corpus work: 0f44617d-26b4-5313-b406-69625775f3e2
DOI: 10.1101/2022.10.20.22281335

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