Article

YTHDF3 modulates the progression of breast cancer cells by regulating FGF2 through m6A methylation

2023-12-14

Abstract excerpt

<h4>Background: </h4> Breast cancer (BC) is a prevailing malignancy among women, and its inconspicuous development contributes significantly to mortality. The RNA N6-methyladenosine (m 6 A) modification represents an emerging mechanism for gene expression regulation, with the active involvement of the YTH N6-methyladenosine RNA binding protein 3 (YTHDF3) in tumor progression across multiple cancer types. Nonethele...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b6233d0b-21ea-5b4f-8970-fdae9b279c05
DOI: 10.21203/rs.3.rs-3721424/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

YTHDF3 modulates the progression of breast cancer cells by regulating FGF2 through m6A methylationDOI 10.21203/rs.3.rs-3721424/v1Read

Genetic identification of the m6A-related gene YTHDF3 as a putative biomarker for breast cancerSemantic proximity Read

Breast cancer intrinsic YTHDF1 forms “cold” tumor and inhibits CD8+ T cells infiltration and functionSemantic proximity Read

Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasisSemantic proximity Read

P4HTM: A Novel Downstream Target of GATA3 in Breast CancerSemantic proximity Read

METTL3 regulates breast cancer-associated alternative splicing switchesSemantic proximity Read

5-methylcytosine profile of mRNA in breast cancer brain metastasisSemantic proximity Read

METTL14 promotes neuroblastoma by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanismSemantic proximity Read

Methylome analysis reveals dysregulated developmental and viral pathways in breast cancerSemantic proximity Read

The three YTHDF paralogs and VIRMA are the major tumor drivers among the m <sup>6</sup> A core genes in a pan-cancer analysisSemantic proximity Read

Pan-Cancer Analysis Identifies YTHDF2 as an Immunological and Prognostic BiomarkerSemantic proximity Read

RNA N6-methyladenosine Reader IGF2BP2 Promotes Lymphatic Metastasis and Epithelial-mesenchymal Transition of Head and Neck Squamous Carcinoma Cells via Stabilizing Slug mRNA in an M6A-dependent MannerSemantic proximity Read

The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translationSemantic proximity Read