Article

Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares

2020-03-12

Abstract excerpt

<title>Abstract</title> <p>Background: Heme oxygenase-1 (HMOX1) catalyzes the metabolism of heme into carbon monoxide, ferrous iron, and biliverdin. Through biliverdin reductase, biliverdin becomes bilirubin. HMOX1-deficiency is a rare autosomal recessive disorder with hallmark features of direct antibody negative hemolytic anemia with normal bilirubin, hyperinflammation and features similar to macrophage activat...

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Literature Corpus work: 0f1741f1-06ea-50c2-abf3-4193ade97a0d
DOI: 10.21203/rs.3.rs-17045/v1

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