Article
Distinct phenotypes and prognosis between Jo-1 and non-Jo-1 subtypes in anti-synthetase syndrome: a retrospective cohort study from China.
Clinical rheumatology - 1 Feb 2026
Zhang Xin, Wang Li, Cheng Qi, Xie Yifan, Wang Fangying, Li Xin, Xue Jing, Du Yan
Abstract excerpt
OBJECTIVE: Anti-synthetase syndrome (ASyS) is characterized by anti-aminoacyl-tRNA synthetase antibodies and heterogeneous multi-organ involvement. This study compared clinical phenotypes and outcomes between Jo-1-positive and non-Jo-1 ASyS patients in a Chinese cohort. METHODS: We retrospectively analyzed 184 ASyS patients treated between June 2017 and December 2020 at a tertiary academic center. Data included...
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