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Article

Adult-onset Still's disease.

Autoimmunity reviews - 1 Jul 2014

Gerfaud-Valentin Mathieu, Jamilloux Yvan, Iwaz Jean, Sève Pascal

Abstract excerpt

First described in 1971, adult-onset Still's disease (AOSD) is a rare multisystemic disorder considered as a complex (multigenic) autoinflammatory syndrome. A genetic background would confer susceptibility to the development of autoinflammatory reactions to environmental triggers. Macrophage and neutrophil activation is a hallmark of AOSD which can lead to a reactive hemophagocytic lymphohistiocytosis. As in the...

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Identifiers

PMID: 24657513
DOI: 10.1016/j.autrev.2014.01.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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