Article

Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares

2020-02-28

Abstract excerpt

<title>Abstract</title> <p>Background Heme oxygenase-1 (HMOX1) catalyzes the metabolism of heme into carbon monoxide, ferrous iron, and biliverdin. Through biliverdin reductase, biliverdin becomes bilirubin. HMOX1 -deficiency is an exceedingly rare autosomal recessive disorder with hallmark features of direct antibody negative hemolytic anemia with normal bilirubin, hyperinflammation and features indicating hemop...

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Literature Corpus work: 43d85842-1d32-5513-a796-f359064a4cf6
DOI: 10.21203/rs.3.rs-15456/v1

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