Article

Bone Marrow Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling

2024-07-05

Abstract excerpt

<h4>ABSTRACT</h4> The bone marrow (BM) is a complex tissue where spatial relationships influence cell behavior, signaling, and function. Consequently, understanding the whole dynamics of cellular interactions requires complementary spatial techniques that preserve and map the architecture of cell populations in situ . We successfully conducted spatial transcriptional profiling using Visium Spatial Gene Expressio...

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Literature Corpus work: 0eff5922-8ed4-5f5d-9546-ef34b82e1761
DOI: 10.1101/2024.07.03.601833

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