Article
Transcriptomic Architecture of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Risk in Mexican Americans.
Cells - 1 Sept 2026
Kumar Satish, Aceves Miriam, Guerra Lorena, Granados Jose, Novilla Earl, Juarez Felicia, Oluwadairo Tolulope, Leandro Ana C, Leandro Marcelo, Peralta Juan, Williams-Blangero Sarah, Blangero John, Curran Joanne E
Abstract excerpt
Hispanics of Mexican American descent in South Texas show a very high prevalence of MASLD, with some studies reporting rates as high as 50% in adults. However, assessment of genetic risk factors underlying this prevalence is complicated by a high co-occurrence of other metabolic disorders and variable endogenous and exogenous environmental risk factors. To map the transcriptomic architecture of MASLD hepatic...
Read the complete abstract on PubMedTopics
- Humans
- Mexican Americans
- Female
- Male
- Transcriptome
- Adult