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Article

Functional non-synonymous polymorphisms prediction methods: current approaches and future developments.

Current medicinal chemistry - 1 Jan 2011

González-Castejón M, Marín F, Soler-Rivas C, Reglero G, Visioli F, Rodríguez-Casado A

Abstract excerpt

Non-synonymous single nucleotide polymorphisms (nsSNPs) are genetic variations that affect the encoded protein by an amino acid change. In humans, many naturally-occurring nsSNPs cause protein dysfunction and increase vulnerability to disease. Identification of such nsSNPs provides an important opportunity to develop drugs/nutrients with precise therapeutic targets. Therefore, current biomedical research and...

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PMID: 22050757
DOI: 10.2174/092986711797636081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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