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Radiation Dosimetry and Fasting-Dependent Hepatobiliary Clearance of the VAChT- Specific PET radioligand 18F-VAT in Humans

2024-12-02

Abstract excerpt

<title>Abstract</title> <p>Background The vesicular acetylcholine transporter ligand (-)-(1-((2R,3R)-8-(2-[(18)F]fluoro-ethoxy)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)piperidin-4-yl)(4-fluorophenyl)-methanone (<sup>18</sup>F -VAT) enables positron emission tomography PET quantification of cholinergic dysfunction in neurologic and psychiatric disorders. Determining its bio-distribution and dose exposure in h...

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Literature Corpus work
0ea472d2-1165-5822-892d-51068bc457bb
DOI
10.21203/rs.3.rs-5375439/v1
Open publication

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Radiation Dosimetry and Fasting-Dependent Hepatobiliary Clearance of the VAChT- Specific PET radioligand 18F-VAT in HumansDOI 10.21203/rs.3.rs-5375439/v1
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