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Aging and putative frailty biomarkers are altered by spaceflight

11 Jun 2024

Abstract excerpt

Human space exploration poses inherent risks to astronauts' health, leading to molecular changes that can significantly impact their well-being. These alterations encompass genomic instability, mitochondrial dysfunction, increased inflammation, homeostatic dysregulation, and various epigenomic changes. Remarkably, these changes bear similarities to those observed during the aging process on Earth. However, our...

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PMID: 38862573
DOI: 10.1038/s41598-024-57948-5

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