Article

Integrative Genetic Analyses of Lipid Metabolism and Multiple Sclerosis Severity Using Metabolome-Wide and Cis-Mendelian Randomization

2026-05-29

Abstract excerpt

<h4>Summary</h4> The course of multiple sclerosis (MS) is highly heterogeneous, yet the biological mechanisms underlying this variability remain incompletely understood. Although metabolic alterations have increasingly been associated with disease progression, existing observational evidence is limited by confounding, reverse causation, and an inability to establish causal mechanisms. To bridge this gap, we used...

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Literature Corpus work: 0e008b80-daa4-5737-a0ff-1d0d390eb9b5
DOI: 10.64898/2026.05.27.26354239

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