Article

Metabolomics reveals lipid and amino acid signatures of disease severity in multiple sclerosis

2026-08-10

Abstract excerpt

<h4>Objective</h4> Plasma metabolomics offers insight into multiple sclerosis (MS) pathophysiology, but existing studies are limited by small sample sizes and incomplete clinical data. <h4>Methods</h4> We conducted plasma metabolomic profiling of 411 deeply phenotyped patients with MS and 46,443 controls, analyzing 162 metabolites in 30 biologically related metabolite groups. We characterized associations with M...

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Literature Corpus work: 96c1334a-23f7-5beb-9704-38c3e37edf42
DOI: 10.64898/2026.08.04.742797

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