Article

Estimating Heritability of Glycaemic Response to Metformin using Nationwide Electronic Health Records and Population-Sized Pedigree

2020-08-25

Abstract excerpt

Variability of response to medication is a well known phenomenon, determined by both environmental and genetic factors. Understanding the heritable component of the response to medication is of great interest but challenging due to several reasons, including small study cohorts and computational limitations. Here, we studied the heritability of variation in the glycaemic response to metformin, first-line therapeut...

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Literature Corpus work: 0df3ac47-883c-542f-adb6-21f09252dc0e
DOI: 10.1101/2020.08.24.20173922

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