Article
An Update on the Pharmacogenomics of Metformin: Progress, Problems and Potential
1 Mar 2014
Abstract excerpt
The increasing prevalence of Type 2 diabetes has emphasized the need to optimize treatment regimens. Metformin, the most widely used oral agent, is recommended as first-line drug therapy by multiple professional organizations. Response to metformin varies significantly at the individual level; this heterogeneity may be explained in part by genetic factors. Understanding these underlying factors may aid with...
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