Article

Genome-wide Analysis Identifies Novel Gallstone-susceptibility Loci Including Genes Regulating Gastrointestinal Motility

2021-07-19

Abstract excerpt

<h4>Objective</h4> Genome-wide association studies (GWAS) have identified several risk loci for gallstone disease. As with most polygenic traits, it is likely many genetic determinants are undiscovered. The aim of this study was to identify novel genetic variants that represent new targets for gallstone research and treatment. <h4>Design</h4> We performed a GWAS of 28,627 gallstone cases and 348,373 controls in...

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Literature Corpus work: 0dca93a1-2d54-5810-a583-aaa0c14da558
DOI: 10.1101/2021.07.16.21260637

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