Article

Transcriptomic profiling of an in vivo diffuse large B-cell lymphoma model reveals molecular programs underlying CNS dissemination

2026-02-18

Abstract excerpt

<title>Abstract</title> <p> Secondary central nervous system involvement (sCNSi) is a fatal complication of diffuse large B-cell lymphoma (DLBCL), yet its molecular determinants remain poorly understood. To investigate the mechanisms underlying CNS-preferential dissemination, we established an <italic>in vivo</italic> DLBCL xenograft model using two representative cell lines, OCI-LY19 and Toledo, followed by t...

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Literature Corpus work: 0dacdf0a-8615-5307-b940-e43fd1a45053
DOI: 10.21203/rs.3.rs-8729569/v1

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