Article
Emerging insights into origin and pathobiology of primary central nervous system lymphoma.
Cancer letters - 1 Jul 2021
You Hua, Wei Li, Kaminska Bozena
Abstract excerpt
Primary central nervous system lymphoma (PCNSL) is an aggressive cancer typically confined to the brain, eyes, leptomeninges and spinal cord, without evidence of systemic involvement. PCNSL remains a challenge for scientists and clinicians due to insufficient biological knowledge, a lack of appropriate animal models and validated diagnostic biomarkers. We summarize recent findings on genomic, transcriptomic and...
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