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Investigating the Role of Neuroinflammation and Brain Clearance in Frontotemporal Lobar Degeneration using 7T MRI and Biofluid Markers: Protocol for an observational cross-sectional cohort study

2025-03-24

Abstract excerpt

<h4>Introduction</h4> Frontotemporal lobar degeneration (FTLD) is the second most common early-onset dementia. Several studies demonstrated that neuroinflammation and iron accumulation occurs in FTLD. However, the timing and relevance of these processes and whether these two are merely cause or consequence remains unclear. Elucidating the role is crucial to assess the rationale for using anti-inflammatory therapie...

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Literature Corpus work: 0da29c0c-339c-51e7-9f80-6e68d8357dd6
DOI: 10.1101/2025.03.24.25324503

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